The Isbell Family, professionally known as "The Isbells," comprises Eric and Rachel Isbell (married November 29, 1997), their daughter Autumn (23), son Kaleb (21), and his wife Abigail (21) (married November 18, 2023).

Initially serving as pastors from June 2000 to March 2013 in four different churches, the Isbells responded to God's calling to utilize their musical talents, including singing, songwriting, and playing various instruments such as the piano, guitar, banjo, fiddle, mandolin, and drums, on the road with their family.

The Isbells have performed in over 2,700 concerts and services, and have made six appearances on the National Quartet Convention's Main Stage since 2018. They have also performed at Dollywood Theme Park and have been featured on the syndicated Christian television shows Gospel Music Showcase and Atlanta Live!